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GSK Reports the P-III Results for Blenrep (belantamab mafodotin) in Combiantion with BorDex (dexamethasone) to Treat Multiple Myeloma

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GSK Reports the P-III Results for Blenrep (belantamab mafodotin) in Combiantion with BorDex (dexamethasone) to Treat Multiple Myeloma

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  • The P-III (DREAMM-7) trial evaluates the safety and efficacy of Blenrep + BorDex vs daratumumab + BorDex as a 2L treatment of patients (n=494) with r/r multiple myeloma. The 1EP of the study includes PFS & 2EPs include OS, DoR & MRD
  • The results depicted a 59% reduction in risk of disease progression or death with Blenrep + BorDex vs daratumumab + BorDex, PFS of 36.6mos. vs 13.4mos., ORR of 82.7% vs 71.3%, CR of 20.6% vs 12%, PR of 16.9% vs 25.1%, MRD rate of 24.7 vs 9.6 & mDoR of 35.6mos. vs 17.8mos. Additionally, the results are expected to be presented at ASCO 2024
  • Blenrep is an ADC comprising a humanized B-cell maturation antigen mAb conjugates with the cytotoxic agent auristatin F via a non-cleavable linker

Ref: GSK | Image: GSK

Related News:- GSK Reports the Results for Blenrep (belantamab mafodotin) in P-III Clinical Trial for the Treatment of Multiple Myeloma

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Shivani Chandra

Shivani is a content writer at PharmaShots. She has a keen interest in recent innovations in the life sciences industry. She covers news related to Product approvals, clinical trial results, and updates. She can be contacted at connect@pharmashots.com.

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